KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNJ11
All Species:
25.15
Human Site:
S354
Identified Species:
61.48
UniProt:
Q14654
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14654
NP_000516
390
43541
S354
R
Q
L
D
E
D
H
S
L
L
E
A
L
T
L
Chimpanzee
Pan troglodytes
XP_521849
390
43540
S354
R
Q
L
D
E
D
R
S
L
L
E
A
L
T
L
Rhesus Macaque
Macaca mulatta
XP_001089155
390
43552
S354
R
Q
L
D
E
D
H
S
L
L
E
A
L
T
L
Dog
Lupus familis
XP_542519
390
43410
S354
R
Q
L
D
E
D
R
S
L
L
D
A
L
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61743
390
43543
S354
R
Q
L
D
E
D
R
S
L
L
D
A
L
T
L
Rat
Rattus norvegicus
P70673
390
43589
S354
R
Q
L
D
E
D
R
S
L
L
D
A
L
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509905
401
44343
S366
R
Q
L
E
E
N
R
S
L
L
D
T
L
P
L
Chicken
Gallus gallus
Q90854
492
55398
L358
K
E
Q
E
E
M
L
L
M
S
S
P
L
I
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001034916
381
42766
R346
A
T
P
N
S
S
A
R
T
L
E
E
A
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52192
505
57401
H440
Y
P
S
T
P
L
N
H
F
Q
S
S
S
N
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.9
97.4
N.A.
96.4
96.1
N.A.
87
37.2
N.A.
70.2
N.A.
N.A.
N.A.
33
N.A.
Protein Similarity:
100
99.7
99.4
98.4
N.A.
97.6
97.6
N.A.
92.7
55.6
N.A.
81.5
N.A.
N.A.
N.A.
51
N.A.
P-Site Identity:
100
93.3
100
86.6
N.A.
86.6
86.6
N.A.
60
13.3
N.A.
13.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
93.3
100
93.3
N.A.
93.3
93.3
N.A.
80
40
N.A.
20
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
10
0
0
0
0
60
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
60
0
60
0
0
0
0
40
0
0
0
0
% D
% Glu:
0
10
0
20
80
0
0
0
0
0
40
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% G
% His:
0
0
0
0
0
0
20
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
70
0
0
10
10
10
70
80
0
0
80
0
70
% L
% Met:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
10
10
0
0
0
0
0
0
10
0
% N
% Pro:
0
10
10
0
10
0
0
0
0
0
0
10
0
10
0
% P
% Gln:
0
70
10
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
70
0
0
0
0
0
50
10
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
10
10
0
70
0
10
20
10
10
0
10
% S
% Thr:
0
10
0
10
0
0
0
0
10
0
0
10
0
60
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _